Kanbé Ogawa and his G・U・I・D・E・ (Global United Infestation Detection and Elimination) team, are deployed by the UN (United Nations) to Tokyo, Japan; to quickly stem a rapidly spreading disease and eliminate the infected.
Yakuza boss TAKIRO KUROKAWA and his daughter, RYOKO KUROKAWA, are discovered, both infected and mutated. Their destination and intentions, shrouded in mystery.